Endothelial Nox5 Expression Modulates Glucose Uptake and Lipid Accumulation in Mice Fed a High-Fat Diet and 3T3-L1 Adipocytes Treated with Glucose and Palmitic Acid

Obesity is a global health issue associated with insulin resistance and altered lipid homeostasis. It has been described that reactive oxygen species (ROS) derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) activity are involved in the development of these pathologies. Th...

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Veröffentlicht in:	International journal of molecular sciences 2021-03, Vol.22 (5), p.2729
Hauptverfasser:	García, Jorge G, Ansorena, Eduardo, Milagro, Fermín I, Zalba, Guillermo, de Miguel, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adipocytes - metabolism Animals Diet, High-Fat - adverse effects Endothelium, Vascular - metabolism Gene Expression Regulation, Enzymologic - drug effects Glucose - metabolism Glucose - pharmacology Lipogenesis - drug effects Lipogenesis - genetics Mice Mice, Transgenic NADPH Oxidase 5 - biosynthesis NADPH Oxidase 5 - genetics Palmitic Acid - pharmacology
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