Notch1 is crucial for decidualization and maintaining the first pregnancy in the mouse

The endometrium undergoes a pregnancy-delivery-repair cycle multiple times during the reproductive lifespan in females. Decidualization is one of the critical events for the success of this essential process. We have previously reported that Notch1 is essential for artificial decidualization in mice...

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Veröffentlicht in:	Biology of reproduction 2021-03, Vol.104 (3), p.539-547
Hauptverfasser:	Wu, Yao, He, Jia-Peng, Xie, Juan, Wang, Ke-Zhi, Kang, Jin-Wen, Fazleabas, Asgerally T., Su, Ren-Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Veterinary - genetics Animals Biology Cell Proliferation Decidua - physiology decidualization Embryo Implantation - genetics Endometrium extracellular matrix Female Females Fertility first pregnancy Gene expression Gene Expression Regulation - physiology Gynecology Hybridization Mice Mice, Knockout Notch1 Notch1 protein Obstetrics Ontology Phosphatase Pregnancy pregnancy loss Pregnancy, Animal - genetics Pregnancy, Animal - metabolism Receptor, Notch1 - genetics Receptor, Notch1 - metabolism RESEARCH ARTICLE Rodents Signal Transduction Transcriptome Uterus Veterinary medicine
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