Maternal protein restriction induces renal AT2R promoter hypomethylation in salt‐sensitive, hypertensive rats

Scope We previously demonstrated that protein restriction in utero induced salt‐sensitive hypertension and changed renal levels of angiotensin type 2 receptor (AT2R) in Stroke‐Prone Spontaneously Hypertensive Rat (SHRSP). Here, we investigated if this characteristic alteration of AT2R is related to...

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Veröffentlicht in:	Food Science & Nutrition 2021-03, Vol.9 (3), p.1452-1459
Hauptverfasser:	Miyoshi, Moe, Imakado, Yasuhisa, Otani, Lila, Kaji, Misa, Aanzai, Yuki, Sugimoto, Naoya, Murakami, Tetsuo, Fukuoka, Masashi, Hohjoh, Hirohiko, Jia, Huijuan, Kato, Hisanori
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Angiotensin AT2 receptors angiotensin type 2 receptor Animals Blood pressure Casein Deoxyribonucleic acid Diet DNA DNA methylation DNA polymerase Fetuses Gene expression Hypertension Kidneys Luciferase maternal protein restriction Methylation Nutrient deficiency Offspring Original Research Plasmids Pregnancy Proteins RNA Saline solutions Salt Salt loading salt sensitivity Salts Stroke‐Prone Spontaneously Hypertensive Rat Transcription
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