Applications of Biomaterials in 3D Cell Culture and Contributions of 3D Cell Culture to Drug Development and Basic Biomedical Research

The process of evaluating the efficacy and toxicity of drugs is important in the production of new drugs to treat diseases. Testing in humans is the most accurate method, but there are technical and ethical limitations. To overcome these limitations, various models have been developed in which respo...

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Veröffentlicht in:	International journal of molecular sciences 2021-03, Vol.22 (5), p.2491
Hauptverfasser:	Park, Yujin, Huh, Kang Moo, Kang, Sun-Woong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Biocompatibility Biocompatible Materials - chemistry Biomaterials Biomedical materials Biomedical Research Cancer Cancer research Cartilage Cell adhesion & migration Cell culture Cell Culture Techniques - methods Collagen Drug Development Drugs External stimuli Fibroblasts Gene expression Genotype & phenotype Humans Hyaluronic acid Hydrogels Mechanical properties Medical research Morphology Neoplasms - drug therapy Neoplasms - pathology Polyethylene glycol Review Stem cells Stem Cells - cytology Stem Cells - drug effects Toxicity
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