Targeting the Renin-Angiotensin-Aldosterone System to Prevent Hypertension and Kidney Disease of Developmental Origins

The renin-angiotensin-aldosterone system (RAAS) is implicated in hypertension and kidney disease. The developing kidney can be programmed by various early-life insults by so-called renal programming, resulting in hypertension and kidney disease in adulthood. This theory is known as developmental ori...

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Veröffentlicht in:	International journal of molecular sciences 2021-02, Vol.22 (5), p.2298
Hauptverfasser:	Hsu, Chien-Ning, Tain, You-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Disease Models, Animal Dysbiosis - metabolism Epigenesis, Genetic Humans Hypertension - genetics Hypertension - metabolism Kidney - growth & development Kidney - metabolism Kidney Diseases - enzymology Kidney Diseases - genetics Kidney Diseases - metabolism Nephrons - cytology Nephrons - growth & development Nephrons - metabolism Nitric Oxide - deficiency Nitric Oxide - metabolism Oxidative Stress - genetics Oxidative Stress - physiology Renin - metabolism Renin-Angiotensin System - genetics Renin-Angiotensin System - physiology Review
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