Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction

The skeletal muscle microenvironment transiently remodels and stiffens after exercise and injury, as muscle ages, and in myopathic muscle; however, how these changes in stiffness affect resident muscle stem cells (MuSCs) remains understudied. Following muscle injury, muscle stiffness remained elevat...

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Veröffentlicht in:	Science advances 2021-03, Vol.7 (11)
Hauptverfasser:	Silver, Jason S, Günay, K Arda, Cutler, Alicia A, Vogler, Thomas O, Brown, Tobin E, Pawlikowski, Bradley T, Bednarski, Olivia J, Bannister, Kendra L, Rogowski, Cameron J, Mckay, Austin G, DelRio, Frank W, Olwin, Bradley B, Anseth, Kristi S
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Biology Materials Science SciAdv r-articles
Online-Zugang:	Volltext
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