Periphery and brain, innate and adaptive immunity in Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder where alpha-synuclein plays a central role in the death and dysfunction of neurons, both, in central, as well as in the peripheral nervous system. Besides the neuronal events observed in patients, PD also includes a significant immune componen...

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Veröffentlicht in:	Acta neuropathologica 2021-04, Vol.141 (4), p.527-545
Hauptverfasser:	Harms, Ashley S., Ferreira, Sara A., Romero-Ramos, Marina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Adaptive Immunity - immunology Animal models Animals Brain - immunology Brain - pathology Central nervous system Humans Immune response Immune system Immunity (Disease) Immunity, Innate - immunology Immunomodulation Inflammation Innate immunity Lymphocytes T Medicine Medicine & Public Health Microglia Monocytes Movement disorders Nervous system Neurodegeneration Neurodegenerative diseases Neuroimmunomodulation - physiology Neurosciences Parkinson Disease - immunology Parkinson Disease - pathology Parkinson's disease Pathology Review Synuclein
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