The role of hyaluronan in wound healing

The polysaccharide hyaluronan (HA) (synonyms – hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's func...

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Veröffentlicht in:	International wound journal 2014-04, Vol.11 (2), p.159-163
1. Verfasser:	Frenkel, Joseph S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - chemistry Adjuvants, Immunologic - physiology Clinical application Dermatology Dermis - cytology Epidermis - cytology Granulation Tissue - physiology Humans Hyaluronan Hyaluronan Clinical application Dermatology Wound healing Wound dressings Hyaluronic Acid - chemistry Hyaluronic Acid - physiology Inflammation - physiopathology Original Re-Epithelialization - physiology Wound dressings Wound healing Wound Healing - physiology
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Beschreibung
Zusammenfassung:	The polysaccharide hyaluronan (HA) (synonyms – hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's function has changed over the years, primarily focussing on a particular aspect or function. The contribution of HA in each stage of normal wound healing as well as its clinical wound dressing applications will be examined.
ISSN:	1742-4801 1742-481X
DOI:	10.1111/j.1742-481X.2012.01057.x