Delivery of eupenifeldin via polymer-coated surgical buttresses prevents local lung cancer recurrence

Lung cancer is the leading cause of cancer deaths worldwide. Unfortunately, high recurrence rates and poor survival remain despite surgical resection and conventional chemotherapy. Local drug delivery systems are a promising intervention for lung cancer treatment with the potential for improved effi...

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Veröffentlicht in:	Journal of controlled release 2021-03, Vol.331, p.260-269
Hauptverfasser:	Al Subeh, Zeinab Y., Chu, Ngoc-Quynh, Korunes-Miller, Jeremy T., Tsai, Lillian L., Graf, Tyler N., Hung, Yin P., Pearce, Cedric J., Grinstaff, Mark W., Colby, Aaron H., Colson, Yolonda L., Oberlies, Nicholas H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer recurrence Drug Delivery Systems Eupenifeldin Humans Local drug delivery Lung Lung cancer Lung Neoplasms - drug therapy Mice Polymer Polymers - therapeutic use Prolonged-release Surgical buttress Tropolone - analogs & derivatives
Online-Zugang:	Volltext
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