Expression of granulocyte-macrophage colony-stimulating factor is regulated by Fli-1 transcription factor, a potential drug target

Friend leukemia virus integration 1 (Fli-1) is an ETS transcription factor and a critical regulator of inflammatory mediators, including MCP-1, CCL5, IL-6, G-CSF, CXCL2, and caspase-1. GM-CSF is a regulator of granulocyte and macrophage lineage differentiation and a key player in the pathogenesis of...

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Veröffentlicht in:	The Journal of immunology (1950) 2020-12, Vol.206 (1), p.59-66
Hauptverfasser:	Wang, Xuan, Richard, Mara Lennard, Li, Pengfei, Henry, Brittany, Schutt, Steven, Yu, Xue-Zhong, Fan, Hongkuan, Zhang, Weiru, Gilkeson, Gary, Zhang, Xian K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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