Atrial fibrillation rhythm is associated with marked changes in metabolic and myofibrillar protein expression in left atrial appendage

Atrial fibrillation (AF) is strongly associated with risk of stroke and heart failure. AF promotes atrial remodeling that increases risk of stroke due to left atrial thrombogenesis, and increases energy demand to support high rate electrical activity and muscle contraction. While many transcriptomic...

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Veröffentlicht in:	Pflügers Archiv 2021-03, Vol.473 (3), p.461-475
Hauptverfasser:	Rennison, Julie H., Li, Ling, Lin, Cheryl R., Lovano, Beth S., Castel, Laurie, Wass, Sojin Youn, Cantlay, Catherine C., McHale, Meghan, Gillinov, A. Marc, Mehra, Reena, Willard, Belinda B., Smith, Jonathan D., Chung, Mina K., Barnard, John, Van Wagoner, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arrhythmia Atrial Appendage - metabolism Atrial Fibrillation - metabolism Biomedical and Life Sciences Biomedicine Cardiac arrhythmia Cell Biology Congestive heart failure Electron transport chain Female Fibrillation Human Physiology Humans Liquid chromatography Male Mass spectroscopy Metabolism Middle Aged Mitochondria Molecular Medicine Muscle contraction Neurosciences Original Article Oxidative phosphorylation Phosphorylation Protein transport Proteins Proteomics Receptors Surgery Tricarboxylic acid cycle
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