Characterization of heteromeric complexes between chemokine (C-X-C motif) receptor 4 and α1-adrenergic receptors utilizing intermolecular bioluminescence resonance energy transfer assays

Recently, we reported that chemokine (C-X-C motif) receptor 4 (CXCR4) heteromerizes with α1-adrenergic receptors (AR) on the cell surface of vascular smooth muscle cells, through which the receptors cross-talk. Direct biophysical evidence for CXCR4:α1-AR heteromers, however, is lacking. Here we util...

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Veröffentlicht in:Biochemical and biophysical research communications 2020-07, Vol.528 (2), p.368-375
Hauptverfasser: Gao, Xianlong, Enten, Garrett A., DeSantis, Anthony J., Volkman, Brian F., Gaponenko, Vadim, Majetschak, Matthias
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Sprache:eng
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