Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research
Abstract Kidney cancer is one of the 10 most common cancers both in the United States and worldwide. Until this year, there had not previously been a conference focused on translational studies in the broad and heterogeneous group of kidney cancers. Therefore, a group of researchers, clinicians, and...
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| Veröffentlicht in: | JNCI : Journal of the National Cancer Institute 2021-03, Vol.113 (3), p.234-243 |
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| creator | Choueiri, Toni K Atkins, Michael B Bakouny, Ziad Carlo, Maria I Drake, Charles G Jonasch, Eric Kapur, Payal Lewis, Bryan Linehan, W Marston Mitchell, Michael J Pal, Sumanta K Pels, Kevin Poteat, Susan Rathmell, W Kimryn Rini, Brian I Signoretti, Sabina Tannir, Nizar Uzzo, Robert Wood, Christopher G Hammers, Hans J |
| description | Abstract
Kidney cancer is one of the 10 most common cancers both in the United States and worldwide. Until this year, there had not previously been a conference focused on translational studies in the broad and heterogeneous group of kidney cancers. Therefore, a group of researchers, clinicians, and patient advocates dedicated to renal cell carcinoma launched the Kidney Cancer Research Summit (KCRS) to spur collaboration and further therapeutic advances in these tumors. This commentary aims to summarize the oral presentations and serve as a record for future iterations of this meeting. The KCRS sessions addressed the tumor microenvironment, novel methods of drug delivery, single cell sequencing strategies, novel immune checkpoint blockade and cellular therapies, predictive biomarkers, and rare variants of kidney cancers. In addition, the meeting included 2 sessions to promote scientific mentoring and kidney cancer research collaborations. A subsequent KCRS will be planned for the fall of 2020. |
| doi_str_mv | 10.1093/jnci/djaa064 |
| format | Article |
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Kidney cancer is one of the 10 most common cancers both in the United States and worldwide. Until this year, there had not previously been a conference focused on translational studies in the broad and heterogeneous group of kidney cancers. Therefore, a group of researchers, clinicians, and patient advocates dedicated to renal cell carcinoma launched the Kidney Cancer Research Summit (KCRS) to spur collaboration and further therapeutic advances in these tumors. This commentary aims to summarize the oral presentations and serve as a record for future iterations of this meeting. The KCRS sessions addressed the tumor microenvironment, novel methods of drug delivery, single cell sequencing strategies, novel immune checkpoint blockade and cellular therapies, predictive biomarkers, and rare variants of kidney cancers. In addition, the meeting included 2 sessions to promote scientific mentoring and kidney cancer research collaborations. A subsequent KCRS will be planned for the fall of 2020.</description><identifier>ISSN: 0027-8874</identifier><identifier>EISSN: 1460-2105</identifier><identifier>DOI: 10.1093/jnci/djaa064</identifier><identifier>PMID: 32359162</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Biomarkers ; Cancer ; Cancer research ; Drug delivery ; Immune checkpoint ; Kidney cancer ; Kidneys ; Medical research ; Renal cell carcinoma ; Translation ; Tumor microenvironment ; Tumors</subject><ispartof>JNCI : Journal of the National Cancer Institute, 2021-03, Vol.113 (3), p.234-243</ispartof><rights>The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com 2020</rights><rights>The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.</rights><rights>The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-60921bdb9a4e7806e0883ee9e6e5ecb9dbf72a0253ca4cb8bfc2ddd4230494e93</citedby><cites>FETCH-LOGICAL-c444t-60921bdb9a4e7806e0883ee9e6e5ecb9dbf72a0253ca4cb8bfc2ddd4230494e93</cites><orcidid>0000-0001-8898-2034 ; 0000-0002-3214-379X ; 0000-0003-0943-2806 ; 0000-0002-6224-4559 ; 0000-0002-4984-0225 ; 0000-0002-9201-3217 ; 0000-0001-5559-8060 ; 0000-0002-9744-9247 ; 0000-0002-3628-2244 ; 0000-0002-2212-080X ; 0000-0002-5000-9105 ; 0000-0003-3901-9924 ; 0000-0003-1906-5704</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,309,310,314,776,780,785,786,881,1578,23909,23910,25118,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32359162$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choueiri, Toni K</creatorcontrib><creatorcontrib>Atkins, Michael B</creatorcontrib><creatorcontrib>Bakouny, Ziad</creatorcontrib><creatorcontrib>Carlo, Maria I</creatorcontrib><creatorcontrib>Drake, Charles G</creatorcontrib><creatorcontrib>Jonasch, Eric</creatorcontrib><creatorcontrib>Kapur, Payal</creatorcontrib><creatorcontrib>Lewis, Bryan</creatorcontrib><creatorcontrib>Linehan, W Marston</creatorcontrib><creatorcontrib>Mitchell, Michael J</creatorcontrib><creatorcontrib>Pal, Sumanta K</creatorcontrib><creatorcontrib>Pels, Kevin</creatorcontrib><creatorcontrib>Poteat, Susan</creatorcontrib><creatorcontrib>Rathmell, W Kimryn</creatorcontrib><creatorcontrib>Rini, Brian I</creatorcontrib><creatorcontrib>Signoretti, Sabina</creatorcontrib><creatorcontrib>Tannir, Nizar</creatorcontrib><creatorcontrib>Uzzo, Robert</creatorcontrib><creatorcontrib>Wood, Christopher G</creatorcontrib><creatorcontrib>Hammers, Hans J</creatorcontrib><title>Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research</title><title>JNCI : Journal of the National Cancer Institute</title><addtitle>J Natl Cancer Inst</addtitle><description>Abstract
Kidney cancer is one of the 10 most common cancers both in the United States and worldwide. Until this year, there had not previously been a conference focused on translational studies in the broad and heterogeneous group of kidney cancers. Therefore, a group of researchers, clinicians, and patient advocates dedicated to renal cell carcinoma launched the Kidney Cancer Research Summit (KCRS) to spur collaboration and further therapeutic advances in these tumors. This commentary aims to summarize the oral presentations and serve as a record for future iterations of this meeting. The KCRS sessions addressed the tumor microenvironment, novel methods of drug delivery, single cell sequencing strategies, novel immune checkpoint blockade and cellular therapies, predictive biomarkers, and rare variants of kidney cancers. In addition, the meeting included 2 sessions to promote scientific mentoring and kidney cancer research collaborations. A subsequent KCRS will be planned for the fall of 2020.</description><subject>Biomarkers</subject><subject>Cancer</subject><subject>Cancer research</subject><subject>Drug delivery</subject><subject>Immune checkpoint</subject><subject>Kidney cancer</subject><subject>Kidneys</subject><subject>Medical research</subject><subject>Renal cell carcinoma</subject><subject>Translation</subject><subject>Tumor microenvironment</subject><subject>Tumors</subject><issn>0027-8874</issn><issn>1460-2105</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kcuKFDEUhoMoTju6cy0BF7rocnKrXFwIQ2OrOCA44zqkUqftaqqSmqRKmJ3v4Bv6JKbptlEXns1ZnI-P8_Mj9JSSV5QYfrELvrtod84RKe6hBRWSVIyS-j5aEMJUpbUSZ-hRzjtSxjDxEJ1xxmtDJVug8XoeBpfu8DrFAU9bwOsu5Ql_7NoAd3jlgoeEP0MGl_wW7-luWuJrGCcYmnKi7Of3H5QvMSPUvMaXeB39nHEM-Ca5kHs3dTG4_qR4jB5sXJ_hyXGfoy_rtzer99XVp3cfVpdXlRdCTJUsn9KmbYwToDSRQLTmAAYk1OAb0zYbxRxhNfdO-EY3G8_athWME2EEGH6O3hy849wM0HoIU3K9HVO3j2uj6-zfl9Bt7df4zSrDJalVEbw8ClK8nSFPduiyh753AeKcLeNGSV0TTQv6_B90F-dUUheqploqoSQv1PJA-RRzTrA5PUOJ3Vdp91XaY5UFf_ZngBP8u7sCvDgAcR7_r_oFeH-pIw</recordid><startdate>20210301</startdate><enddate>20210301</enddate><creator>Choueiri, Toni K</creator><creator>Atkins, Michael B</creator><creator>Bakouny, Ziad</creator><creator>Carlo, Maria I</creator><creator>Drake, Charles G</creator><creator>Jonasch, Eric</creator><creator>Kapur, Payal</creator><creator>Lewis, Bryan</creator><creator>Linehan, W Marston</creator><creator>Mitchell, Michael J</creator><creator>Pal, Sumanta K</creator><creator>Pels, Kevin</creator><creator>Poteat, Susan</creator><creator>Rathmell, W Kimryn</creator><creator>Rini, Brian I</creator><creator>Signoretti, Sabina</creator><creator>Tannir, Nizar</creator><creator>Uzzo, Robert</creator><creator>Wood, Christopher G</creator><creator>Hammers, Hans J</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8898-2034</orcidid><orcidid>https://orcid.org/0000-0002-3214-379X</orcidid><orcidid>https://orcid.org/0000-0003-0943-2806</orcidid><orcidid>https://orcid.org/0000-0002-6224-4559</orcidid><orcidid>https://orcid.org/0000-0002-4984-0225</orcidid><orcidid>https://orcid.org/0000-0002-9201-3217</orcidid><orcidid>https://orcid.org/0000-0001-5559-8060</orcidid><orcidid>https://orcid.org/0000-0002-9744-9247</orcidid><orcidid>https://orcid.org/0000-0002-3628-2244</orcidid><orcidid>https://orcid.org/0000-0002-2212-080X</orcidid><orcidid>https://orcid.org/0000-0002-5000-9105</orcidid><orcidid>https://orcid.org/0000-0003-3901-9924</orcidid><orcidid>https://orcid.org/0000-0003-1906-5704</orcidid></search><sort><creationdate>20210301</creationdate><title>Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research</title><author>Choueiri, Toni K ; 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Kidney cancer is one of the 10 most common cancers both in the United States and worldwide. Until this year, there had not previously been a conference focused on translational studies in the broad and heterogeneous group of kidney cancers. Therefore, a group of researchers, clinicians, and patient advocates dedicated to renal cell carcinoma launched the Kidney Cancer Research Summit (KCRS) to spur collaboration and further therapeutic advances in these tumors. This commentary aims to summarize the oral presentations and serve as a record for future iterations of this meeting. The KCRS sessions addressed the tumor microenvironment, novel methods of drug delivery, single cell sequencing strategies, novel immune checkpoint blockade and cellular therapies, predictive biomarkers, and rare variants of kidney cancers. In addition, the meeting included 2 sessions to promote scientific mentoring and kidney cancer research collaborations. A subsequent KCRS will be planned for the fall of 2020.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>32359162</pmid><doi>10.1093/jnci/djaa064</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-8898-2034</orcidid><orcidid>https://orcid.org/0000-0002-3214-379X</orcidid><orcidid>https://orcid.org/0000-0003-0943-2806</orcidid><orcidid>https://orcid.org/0000-0002-6224-4559</orcidid><orcidid>https://orcid.org/0000-0002-4984-0225</orcidid><orcidid>https://orcid.org/0000-0002-9201-3217</orcidid><orcidid>https://orcid.org/0000-0001-5559-8060</orcidid><orcidid>https://orcid.org/0000-0002-9744-9247</orcidid><orcidid>https://orcid.org/0000-0002-3628-2244</orcidid><orcidid>https://orcid.org/0000-0002-2212-080X</orcidid><orcidid>https://orcid.org/0000-0002-5000-9105</orcidid><orcidid>https://orcid.org/0000-0003-3901-9924</orcidid><orcidid>https://orcid.org/0000-0003-1906-5704</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Oxford University Press Journals All Titles (1996-Current); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Biomarkers Cancer Cancer research Drug delivery Immune checkpoint Kidney cancer Kidneys Medical research Renal cell carcinoma Translation Tumor microenvironment Tumors |
| title | Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research |
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