Ppp1r3d deficiency preferentially inhibits neuronal and cardiac Lafora body formation in a mouse model of the fatal epilepsy Lafora disease

Mammalian glycogen chain lengths are subject to complex regulation, including by seven proteins (protein phosphatase‐1 regulatory subunit 3, PPP1R3A through PPP1R3G) that target protein phosphatase‐1 (PP1) to glycogen to activate the glycogen chain‐elongating enzyme glycogen synthase and inactivate...

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Veröffentlicht in:Journal of neurochemistry 2021-06, Vol.157 (6), p.1897-1910
Hauptverfasser: Israelian, Lori, Nitschke, Silvia, Wang, Peixiang, Zhao, Xiaochu, Perri, Ami M., Lee, Jennifer P.Y., Verhalen, Brandy, Nitschke, Felix, Minassian, Berge A.
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