Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study)

Background Fibroblast growth factor receptor 2 ( FGFR2 ) rearrangement is expected to be a novel therapeutic target in advanced/recurrent biliary tract cancer (BTC). However, efficient detection and the exact frequency of FGFR2 rearrangements among patients with advanced/recurrent BTC have not been...

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Veröffentlicht in:	Journal of gastroenterology 2021-03, Vol.56 (3), p.250-260
Hauptverfasser:	Maruki, Yuta, Morizane, Chigusa, Arai, Yasuhito, Ikeda, Masafumi, Ueno, Makoto, Ioka, Tatsuya, Naganuma, Atsushi, Furukawa, Masayuki, Mizuno, Nobumasa, Uwagawa, Tadashi, Takahara, Naminatsu, Kanai, Masashi, Asagi, Akinori, Shimizu, Satoshi, Miyamoto, Atsushi, Yukisawa, Seigo, Kadokura, Makoto, Kojima, Yasushi, Furuse, Junji, Nakajima, Takako Eguchi, Sudo, Kentaro, Kobayashi, Noritoshi, Hama, Natsuko, Yamanaka, Takeharu, Shibata, Tatsuhiro, Okusaka, Takuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Analysis Biliary Tract Biopsy Carcinoma Cholangiocarcinoma Colorectal Surgery Cytogenetics Fibroblast growth factor receptor 2 Fluorescence in situ hybridization Formaldehyde Gastroenterology Health aspects Hepatitis Hepatology Medicine Medicine & Public Health Observational studies Original Article—Liver Original —Liver, Pancreas, and Biliary Tract Pancreas Paraffin Ribonucleic acid RNA RNA sequencing Surgical Oncology Therapeutic targets
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