Taccalonolides: A Novel Class of Microtubule-Stabilizing Anticancer Agents

Microtubule stabilizing agents, such as paclitaxel, docetaxel, and cabazitaxel have been among the most used chemotherapeutic agents in the last decades for the treatment of a wide range of cancers in the clinic. One of the concerns that limit their use in clinical practice is their intrinsic and ac...

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Veröffentlicht in:	Cancers 2021-02, Vol.13 (4), p.920
Hauptverfasser:	Chen, Xiaoyan, Winstead, Angela, Yu, Hongtao, Peng, Jiangnan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitumor agents Binding sites Biosynthesis Cancer Chemotherapy Drug resistance Herbal medicine Microtubules Paclitaxel Polymerization Review Structure-activity relationships Tubulin X-ray diffraction
Online-Zugang:	Volltext
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