Drug-induced Hypersensitivity Syndrome by EGFR-TKI in a Patient with Lung Cancer

An 83-years-old woman diagnosed with advanced Epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma was administered afatinib as a first-line treatment. On Day 17, the patient presented with grade 3 diarrhea and a blood test analysis showed an increased inflammatory response. Afatinib t...

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Veröffentlicht in:	Internal Medicine 2021/02/01, Vol.60(3), pp.441-444
Hauptverfasser:	Oyama, Baku, Morikawa, Kei, Sakaguchi, Tadashi, Tsunoda, Akihito, Kida, Hirotaka, Inoue, Takeo, Mineshita, Masamichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma of Lung - drug therapy afatinib Afatinib - adverse effects Aged, 80 and over Blood tests Case Report Diarrhea drug-induced hypersensitivity syndrome Epidermal growth factor Epidermal growth factor receptors ErbB Receptors - genetics Erythema Female HHV-6 Humans Hypersensitivity Inflammation Internal medicine Lung cancer Lung Neoplasms - drug therapy Mutation Pharmaceutical Preparations Prednisolone
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