TET3 regulates DNA hydroxymethylation of neuroprotective genes following focal ischemia

The 5-hydroxymethylcytosine (5hmC) epigenetic modification is highly enriched in the CNS and a critical modulator of neuronal function and development. We found that cortical 5hmC was enhanced from 5 min to three days of reperfusion following focal ischemia in adult mice. Blockade of the 5hmC-produc...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2021-03, Vol.41 (3), p.590-603
Hauptverfasser:	Morris-Blanco, Kahlilia C, Chokkalla, Anil K, Bertogliat, Mario J, Vemuganti, Raghu
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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