Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression

Kidney involvement in systemic lupus erythematosus (SLE)-termed lupus nephritis (LN)-is a severe manifestation of SLE that can lead to end-stage kidney disease (ESKD). LN is characterized by immune complex deposition and inflammation in the glomerulus. We tested the hypothesis that autoantibodies ta...

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Veröffentlicht in:	Journal of clinical medicine 2021-02, Vol.10 (4), p.793
Hauptverfasser:	Caster, Dawn J, Korte, Erik A, Merchant, Michael L, Klein, Jon B, Barati, Michelle T, Joglekar, Ami, Wilkey, Daniel W, Coventry, Susan, Hata, Jessica, Rovin, Brad H, Harley, John B, Namjou-Khales, Bahram, McLeish, Kenneth R, Powell, David W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Biopsy Biotechnology Blood & organ donations Clinical medicine Cybernetics Kidney diseases Lupus Mass spectrometry Membranes Proteins Scientific imaging Software Variance analysis
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