A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes
A closed-loop system (also called an artificial pancreas) may improve glycemic outcomes in children with type 1 diabetes. In this 16-week trial, the glucose level was in the target range for a greater percentage of time with a closed-loop system than with a sensor-augmented insulin pump.
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| Veröffentlicht in: | The New England journal of medicine 2020-08, Vol.383 (9), p.836-845 |
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| container_title | The New England journal of medicine |
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| creator | Breton, Marc D Kanapka, Lauren G Beck, Roy W Ekhlaspour, Laya Forlenza, Gregory P Cengiz, Eda Schoelwer, Melissa Ruedy, Katrina J Jost, Emily Carria, Lori Emory, Emma Hsu, Liana J Oliveri, Mary Kollman, Craig C Dokken, Betsy B Weinzimer, Stuart A DeBoer, Mark D Buckingham, Bruce A Cherñavvsky, Daniel Wadwa, R. Paul |
| description | A closed-loop system (also called an artificial pancreas) may improve glycemic outcomes in children with type 1 diabetes. In this 16-week trial, the glucose level was in the target range for a greater percentage of time with a closed-loop system than with a sensor-augmented insulin pump. |
| doi_str_mv | 10.1056/NEJMoa2004736 |
| format | Article |
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Paul</creatorcontrib><creatorcontrib>iDCL Trial Research Group</creatorcontrib><title>A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>A closed-loop system (also called an artificial pancreas) may improve glycemic outcomes in children with type 1 diabetes. 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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2020-08, Vol.383 (9), p.836-845 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | Adolescent Age Automation Blood Glucose Blood Glucose - analysis Child Children Closed loop systems Diabetes Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Diabetic Ketoacidosis Diabetic Ketoacidosis - etiology FDA approval Female Glucose Glycated Hemoglobin A Glycated Hemoglobin A - analysis Hemoglobin Human health and pathology Humans Hypoglycemia Hypoglycemia - chemically induced Hypoglycemic Agents Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - adverse effects Infusion Pumps, Implantable Injections, Subcutaneous Insulin Insulin - administration & dosage Insulin - adverse effects Insulin Infusion Systems Insulin Infusion Systems - adverse effects Ketoacidosis Kidney diseases Laboratories Life Sciences Male Pancreas Pancreas, Artificial Patients Quality of life Statistical analysis |
| title | A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes |
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