Survival after extracorporeal membrane oxygenation in severe COVID-19 ARDS: results from an international multicenter registry

At the participating centers, all patients with reverse transcriptase polymerase chain reaction (rtPCR) positive testing for SARS-CoV-2, who received V-V ECMO from March 12 to June 5, 2020 (i.e., during the first wave of the pandemic), were included. [...]even though 90-day-survival of patients aged...

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Veröffentlicht in:Critical care (London, England) England), 2021-03, Vol.25 (1), p.90-90, Article 90
Hauptverfasser: Supady, Alexander, Taccone, Fabio Silvio, Lepper, Philipp M., Ziegeler, Stephan, Staudacher, Dawid L.
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container_title Critical care (London, England)
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creator Supady, Alexander
Taccone, Fabio Silvio
Lepper, Philipp M.
Ziegeler, Stephan
Staudacher, Dawid L.
description At the participating centers, all patients with reverse transcriptase polymerase chain reaction (rtPCR) positive testing for SARS-CoV-2, who received V-V ECMO from March 12 to June 5, 2020 (i.e., during the first wave of the pandemic), were included. [...]even though 90-day-survival of patients aged ≥ 71 years was significantly lower than for patients 
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[...]even though 90-day-survival of patients aged ≥ 71 years was significantly lower than for patients &lt; 71 years, not all treatments in this elderly population ended fatal. [...]age limits should be viewed with caution and decisions for or against the use of ECMO for patients above 70 years of age should be performed on an individual case-by-case level. [...]our data may support the use of V-V ECMO in severe COVID-19 ARDS, also after prolonged periods of mechanical ventilation in selected patients. Collaborating authors (COVEC-study group): Jeff DellaVolpe, Methodist Hospital, San Antonio, Texas, USA; Dominik Scharpf, SLK-Hospital Heilbronn, Germany; Matthias Ulmer, RKH Hospital Ludwigsburg, Germany; Maximilian Halbe, Heart Center, University Hospital Zurich, Switzerland; Alexander Vogt, Department of Medicine III, University Clinic Halle (Saale), Germany; Raj Ramanan, University of Pittsburgh Medical Center (UPMC), Pennsylvania, USA; David Boldt, UCLA Healthcare System, Los Angeles, USA; Stephanie-Susanne Stecher, Medical Department II, LMU Hospital Munich, Germany; Andrea Montisci, Istituto Clinico Sant’Ambrogio, University of Milan, Italy; Tobias Spangenberg, Department of Cardiology, Angiology and Intensive Care, Marien Hospital Hamburg, Germany; Olivier Marggraf, Asklepios Clinic North, Hamburg, Germany; Chandra Kunavarapu, Methodist Hospital, San Antonio, Texas, USA; Lorenzo Peluso, Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium; Sebastian Muenz, SLK-Hospital Heilbronn, Germany; Monica Buerle, RKH Hospital Ludwigsburg, Germany; Naveen G. Nagaraj, Heart Center, University Hospital Zurich, Switzerland; Sebastian Nuding, Department of Medicine III, University Clinic Halle (Saale), Germany; Catalin Toma, University of Pittsburgh Medical Center (UPMC), Pennsylvania, USA; Vadim Gudzenko, UCLA Healthcare System, Los Angeles, USA; Hans Joachim Stemmler, Medical Department III, LMU Hospital Munich, Germany; Federico Pappalardo, Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Palermo, Italy; Georg Trummer, Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Germany; Christoph Benk, Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Germany; Guido Michels, Department of Acute and Emergency Care, St. Antonius Hospital Eschweiler, Eschweiler, Germany; Christoph Bode, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Daniel Duerschmied, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Constantin von zur Muehlen, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Klaus Kaier, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany, Institute of Medical Biometry and Statistics, Faculty of Medicine, University of Freiburg, Germany, Daniel Brodie, Columbia University College of Physicians &amp; Surgeons/New York-Presbyterian Hospital, New York, USA, Center for Acute Respiratory Failure, Columbia University Medical Center, New York, USA; Tobias Wengenmayer, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany.</description><identifier>ISSN: 1364-8535</identifier><identifier>EISSN: 1466-609X</identifier><identifier>EISSN: 1364-8535</identifier><identifier>EISSN: 1366-609X</identifier><identifier>DOI: 10.1186/s13054-021-03486-9</identifier><identifier>PMID: 33648538</identifier><language>eng</language><publisher>LONDON: Springer Nature</publisher><subject>Acute respiratory distress syndrome ; Aged ; Attorneys ; Blood oxygenation, Extracorporeal ; Cardiology ; Care and treatment ; Coronaviruses ; COVID-19 ; COVID-19 - diagnosis ; COVID-19 - mortality ; COVID-19 - therapy ; Critical care ; Critical Care Medicine ; Extracorporeal membrane oxygenation ; Extracorporeal Membrane Oxygenation - mortality ; Extracorporeal Membrane Oxygenation - trends ; Female ; General &amp; Internal Medicine ; Heart surgery ; Hospitals ; Humans ; Intensive care ; Interdisciplinary aspects ; Internationality ; Life Sciences &amp; Biomedicine ; Male ; Medicine ; Middle Aged ; Patient outcomes ; Registries ; Research Letter ; Respiratory distress syndrome ; Respiratory Distress Syndrome - diagnosis ; Respiratory Distress Syndrome - mortality ; Respiratory Distress Syndrome - therapy ; Retrospective Studies ; Science &amp; Technology ; Severe acute respiratory syndrome coronavirus 2 ; Survival Rate - trends ; Ventilators</subject><ispartof>Critical care (London, England), 2021-03, Vol.25 (1), p.90-90, Article 90</ispartof><rights>COPYRIGHT 2021 BioMed Central Ltd.</rights><rights>2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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[...]even though 90-day-survival of patients aged ≥ 71 years was significantly lower than for patients &lt; 71 years, not all treatments in this elderly population ended fatal. [...]age limits should be viewed with caution and decisions for or against the use of ECMO for patients above 70 years of age should be performed on an individual case-by-case level. [...]our data may support the use of V-V ECMO in severe COVID-19 ARDS, also after prolonged periods of mechanical ventilation in selected patients. Collaborating authors (COVEC-study group): Jeff DellaVolpe, Methodist Hospital, San Antonio, Texas, USA; Dominik Scharpf, SLK-Hospital Heilbronn, Germany; Matthias Ulmer, RKH Hospital Ludwigsburg, Germany; Maximilian Halbe, Heart Center, University Hospital Zurich, Switzerland; Alexander Vogt, Department of Medicine III, University Clinic Halle (Saale), Germany; Raj Ramanan, University of Pittsburgh Medical Center (UPMC), Pennsylvania, USA; David Boldt, UCLA Healthcare System, Los Angeles, USA; Stephanie-Susanne Stecher, Medical Department II, LMU Hospital Munich, Germany; Andrea Montisci, Istituto Clinico Sant’Ambrogio, University of Milan, Italy; Tobias Spangenberg, Department of Cardiology, Angiology and Intensive Care, Marien Hospital Hamburg, Germany; Olivier Marggraf, Asklepios Clinic North, Hamburg, Germany; Chandra Kunavarapu, Methodist Hospital, San Antonio, Texas, USA; Lorenzo Peluso, Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium; Sebastian Muenz, SLK-Hospital Heilbronn, Germany; Monica Buerle, RKH Hospital Ludwigsburg, Germany; Naveen G. Nagaraj, Heart Center, University Hospital Zurich, Switzerland; Sebastian Nuding, Department of Medicine III, University Clinic Halle (Saale), Germany; Catalin Toma, University of Pittsburgh Medical Center (UPMC), Pennsylvania, USA; Vadim Gudzenko, UCLA Healthcare System, Los Angeles, USA; Hans Joachim Stemmler, Medical Department III, LMU Hospital Munich, Germany; Federico Pappalardo, Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Palermo, Italy; Georg Trummer, Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Germany; Christoph Benk, Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Germany; Guido Michels, Department of Acute and Emergency Care, St. Antonius Hospital Eschweiler, Eschweiler, Germany; Christoph Bode, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Daniel Duerschmied, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Constantin von zur Muehlen, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Klaus Kaier, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany, Institute of Medical Biometry and Statistics, Faculty of Medicine, University of Freiburg, Germany, Daniel Brodie, Columbia University College of Physicians &amp; Surgeons/New York-Presbyterian Hospital, New York, USA, Center for Acute Respiratory Failure, Columbia University Medical Center, New York, USA; Tobias Wengenmayer, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany.</description><subject>Acute respiratory distress syndrome</subject><subject>Aged</subject><subject>Attorneys</subject><subject>Blood oxygenation, Extracorporeal</subject><subject>Cardiology</subject><subject>Care and treatment</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - diagnosis</subject><subject>COVID-19 - mortality</subject><subject>COVID-19 - therapy</subject><subject>Critical care</subject><subject>Critical Care Medicine</subject><subject>Extracorporeal membrane oxygenation</subject><subject>Extracorporeal Membrane Oxygenation - mortality</subject><subject>Extracorporeal Membrane Oxygenation - trends</subject><subject>Female</subject><subject>General &amp; 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[...]even though 90-day-survival of patients aged ≥ 71 years was significantly lower than for patients &lt; 71 years, not all treatments in this elderly population ended fatal. [...]age limits should be viewed with caution and decisions for or against the use of ECMO for patients above 70 years of age should be performed on an individual case-by-case level. [...]our data may support the use of V-V ECMO in severe COVID-19 ARDS, also after prolonged periods of mechanical ventilation in selected patients. Collaborating authors (COVEC-study group): Jeff DellaVolpe, Methodist Hospital, San Antonio, Texas, USA; Dominik Scharpf, SLK-Hospital Heilbronn, Germany; Matthias Ulmer, RKH Hospital Ludwigsburg, Germany; Maximilian Halbe, Heart Center, University Hospital Zurich, Switzerland; Alexander Vogt, Department of Medicine III, University Clinic Halle (Saale), Germany; Raj Ramanan, University of Pittsburgh Medical Center (UPMC), Pennsylvania, USA; David Boldt, UCLA Healthcare System, Los Angeles, USA; Stephanie-Susanne Stecher, Medical Department II, LMU Hospital Munich, Germany; Andrea Montisci, Istituto Clinico Sant’Ambrogio, University of Milan, Italy; Tobias Spangenberg, Department of Cardiology, Angiology and Intensive Care, Marien Hospital Hamburg, Germany; Olivier Marggraf, Asklepios Clinic North, Hamburg, Germany; Chandra Kunavarapu, Methodist Hospital, San Antonio, Texas, USA; Lorenzo Peluso, Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium; Sebastian Muenz, SLK-Hospital Heilbronn, Germany; Monica Buerle, RKH Hospital Ludwigsburg, Germany; Naveen G. Nagaraj, Heart Center, University Hospital Zurich, Switzerland; Sebastian Nuding, Department of Medicine III, University Clinic Halle (Saale), Germany; Catalin Toma, University of Pittsburgh Medical Center (UPMC), Pennsylvania, USA; Vadim Gudzenko, UCLA Healthcare System, Los Angeles, USA; Hans Joachim Stemmler, Medical Department III, LMU Hospital Munich, Germany; Federico Pappalardo, Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Palermo, Italy; Georg Trummer, Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Germany; Christoph Benk, Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Germany; Guido Michels, Department of Acute and Emergency Care, St. Antonius Hospital Eschweiler, Eschweiler, Germany; Christoph Bode, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Daniel Duerschmied, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Constantin von zur Muehlen, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany; Klaus Kaier, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany, Institute of Medical Biometry and Statistics, Faculty of Medicine, University of Freiburg, Germany, Daniel Brodie, Columbia University College of Physicians &amp; Surgeons/New York-Presbyterian Hospital, New York, USA, Center for Acute Respiratory Failure, Columbia University Medical Center, New York, USA; Tobias Wengenmayer, Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Germany, Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Germany.</abstract><cop>LONDON</cop><pub>Springer Nature</pub><pmid>33648538</pmid><doi>10.1186/s13054-021-03486-9</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0003-4056-3652</orcidid><oa>free_for_read</oa></addata></record>
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identifier ISSN: 1364-8535
ispartof Critical care (London, England), 2021-03, Vol.25 (1), p.90-90, Article 90
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1466-609X
1364-8535
1366-609X
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source MEDLINE; DOAJ Directory of Open Access Journals; Springer Journals; SpringerOpen (Open Access); Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; Free E-Journal (出版社公開部分のみ); PubMed Central; Alma/SFX Local Collection
subjects Acute respiratory distress syndrome
Aged
Attorneys
Blood oxygenation, Extracorporeal
Cardiology
Care and treatment
Coronaviruses
COVID-19
COVID-19 - diagnosis
COVID-19 - mortality
COVID-19 - therapy
Critical care
Critical Care Medicine
Extracorporeal membrane oxygenation
Extracorporeal Membrane Oxygenation - mortality
Extracorporeal Membrane Oxygenation - trends
Female
General & Internal Medicine
Heart surgery
Hospitals
Humans
Intensive care
Interdisciplinary aspects
Internationality
Life Sciences & Biomedicine
Male
Medicine
Middle Aged
Patient outcomes
Registries
Research Letter
Respiratory distress syndrome
Respiratory Distress Syndrome - diagnosis
Respiratory Distress Syndrome - mortality
Respiratory Distress Syndrome - therapy
Retrospective Studies
Science & Technology
Severe acute respiratory syndrome coronavirus 2
Survival Rate - trends
Ventilators
title Survival after extracorporeal membrane oxygenation in severe COVID-19 ARDS: results from an international multicenter registry
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