Melanoma brain metastases have lower T-cell content and microvessel density compared to matched extracranial metastases

Background Although melanoma brain metastases (MBM) tend to respond to systemic therapy concordantly with extracranial metastases, little is known about differences in immune cell and vascular content between the brain and other metastatic sites. Here we studied infiltrating immune cell subsets and...

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Veröffentlicht in:Journal of neuro-oncology 2021-03, Vol.152 (1), p.15-25
Hauptverfasser: Weiss, Sarah A., Zito, Christopher, Tran, Thuy, Heishima, Kazuki, Neumeister, Veronique, McGuire, John, Adeniran, Adebowale, Kluger, Harriet, Jilaveanu, Lucia B.
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Sprache:eng
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