BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells

The basic leucine zipper ATF-like transcription factor 2 (BATF2) has been implicated in inflammatory responses and anti-tumour effects. Little, however, is known regarding its extracellular role in maintaining a non-supportive cancer microenvironment. Here, we show that BATF2 inhibits glioma growth...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncogene 2021-02, Vol.40 (8), p.1516-1530
Hauptverfasser:	Zhang, Xin, Liu, Yi, Dai, Lei, Shi, Gang, Deng, Jie, Luo, Qiang, Xie, Qian, Cheng, Lin, Li, Chunlei, Lin, Yi, Wang, Qingnan, Fan, Ping, Zhang, Hantao, Su, Xiaolan, Zhang, Shuang, Yang, Yang, Hu, Xun, Gong, Qiyong, Yu, Dechao, Zheng, Lei, Deng, Hongxin
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/106 13/109 13/21 13/51 13/56 13/89 14/19 14/28 38/44 59/57 631/67/1857 631/80 64/60 9/10 96/31 Adult Aged Animals Apoptosis Basic-Leucine Zipper Transcription Factors - genetics Benzylamines - pharmacology Bone marrow cells Brain cancer Care and treatment Cell Biology Cell Line, Tumor Cell Migration Inhibition - genetics Cellular signal transduction Chemokine CXCL12 - genetics Chemotaxis CXCR4 protein Cyclams - pharmacology Development and progression Extracellular vesicles Female Gene Expression Regulation, Neoplastic - drug effects Genetic aspects Glioblastoma Glioblastoma - blood Glioblastoma - genetics Glioblastoma - pathology Glioblastoma multiforme Glioma cells Health aspects Heterografts Human Genetics Humans Inflammation Internal Medicine Leucine zipper proteins Male Medicine Medicine & Public Health Mice Microenvironments Middle Aged Myeloid-Derived Suppressor Cells - metabolism Myeloid-Derived Suppressor Cells - pathology Neoplasm Staging Oncology Receptors, CXCR4 - genetics Recruitment Signal Transduction - drug effects Stem cells Suppressor cells Transcription factors Tumor Microenvironment - drug effects Tumor Suppressor Proteins - genetics Tumors Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!