Chimeric antigen receptor-natural killer cells: Novel insight into immunotherapy for solid tumors (Review)

The chimeric antigen receptor (CAR) is an artificially modified fusion protein consisting of an extracellular antigen-binding domain, transmembrane domain and intracellular signalling domain. CAR-T therapy has demonstrated remarkable clinical efficacy in hematological malignancies. However, cytokine...

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Veröffentlicht in:	Experimental and therapeutic medicine 2021-04, Vol.21 (4), p.340-340, Article 340
Hauptverfasser:	Peng, Xiaobo, Chen, Ling, Chen, Longpei, Wang, Bin, Wang, Yiran, Zhan, Xianbao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Blood cancer Bone marrow Cancer Care and treatment Cell adhesion & migration Colorectal cancer Cytokines Cytotoxicity Dendritic cells Health aspects Immune system Immunoglobulins Immunotherapy Innovations Killer cells Lymphocytes Metastasis Methods Ovarian cancer Physiological aspects Prostate cancer Review Signal transduction Stem cells Tumors Vectors (Biology)
Online-Zugang:	Volltext
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