CtIP-mediated alternative mRNA splicing fine-tunes the DNA damage response

In order to survive to the exposure of DNA damaging agents, cells activate a complex response that coordinates the cellular metabolism, cell cycle progression, and DNA repair. Among many other events, recent evidence has described global changes in mRNA splicing in cells treated with genotoxic agent...

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Veröffentlicht in:	RNA (Cambridge) 2021-03, Vol.27 (3), p.303-323
Hauptverfasser:	Prados-Carvajal, Rosario, Rodríguez-Real, Guillermo, Gutierrez-Pozo, Gabriel, Huertas, Pablo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative splicing Cell cycle Deoxyribonucleic acid DNA DNA damage DNA helicase DNA repair Genotoxicity Ionizing radiation mRNA Splicing factors
Online-Zugang:	Volltext
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