Effects of Blood Components and Whole Blood in a Model of Severe Trauma-Induced Coagulopathy

Plasma resuscitation ameliorates hyperfibrinolysis (HF) and trauma-induced coagulopathy (TIC). However, the use of other blood components to reduce HF has not been evaluated. Therefore, our aim was to determine the effect of individual blood components and whole blood (WB) on an in vitro model of se...

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Veröffentlicht in:	The Journal of surgical research 2021-03, Vol.259, p.55-61
Hauptverfasser:	Stettler, Gregory R., Moore, Ernest E., Nunns, Geoffrey R., Kelher, Marguerite, Banerjee, Anirban, Silliman, Christopher C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Coagulation Disorders - blood Blood Coagulation Disorders - diagnosis Blood Coagulation Disorders - etiology Blood Coagulation Disorders - therapy Blood component therapy Blood Component Transfusion - methods Healthy Volunteers Humans Hyperfibrinolysis In Vitro Techniques Resuscitation - methods Thrombelastography Tissue Plasminogen Activator - blood Tissue Plasminogen Activator - metabolism Trauma Severity Indices Trauma-induced coagulopathy Whole blood Wounds and Injuries - blood Wounds and Injuries - complications Wounds and Injuries - diagnosis
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