An unusual cause of fever and jaundice

An unusual cause of fever and jaundice

A 52 year old previously healthy woman from Mumbai presented with fever and jaundice of 10 days duration. At admission, she was jaundiced with tachycardia, tachypnea, hypoxia, hypotension, conjunctival congestion and mild erythematous flush over the skin. She had very high WBC counts and CRP's...

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Veröffentlicht in:Indian journal of medical microbiology 2021-07, Vol.39 (3), p.320-322
Hauptverfasser: Varyani, Umesh, Singhal, Tanu, Sheth, Sharad, Shetty, Kiran, Harshe, Pradnya, Shah, Sweta
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Adults
MIS-A
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container_end_page 322
container_issue 3
container_start_page 320
container_title Indian journal of medical microbiology
container_volume 39
creator Varyani, Umesh
Singhal, Tanu
Sheth, Sharad
Shetty, Kiran
Harshe, Pradnya
Shah, Sweta
description A 52 year old previously healthy woman from Mumbai presented with fever and jaundice of 10 days duration. At admission, she was jaundiced with tachycardia, tachypnea, hypoxia, hypotension, conjunctival congestion and mild erythematous flush over the skin. She had very high WBC counts and CRP's with direct hyperbilirubinemia and azotemia. Investigations for infectious causes of fever were negative. RT-PCR for SARS-CoV-2 in the nasopharynx was negative. However her SARS-CoV-2 antibodies were reactive. She also had echocardiographic and biochemical evidence of cardiac dysfunction. The diagnosis of Multisystem inflammatory syndrome–Adult (MIS-A) was thus established. She rapidly improved with intravenous immunoglobulin (2 gm/kg) and high dose steroids.
doi_str_mv 10.1016/j.ijmmb.2021.02.001
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ispartof Indian journal of medical microbiology, 2021-07, Vol.39 (3), p.320-322
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1998-3646
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subjects Adults
MIS-A
Original
title An unusual cause of fever and jaundice
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