Reference Standardization for Quantification and Harmonization of Large-Scale Metabolomics

Reference standardization was developed to address quantification and harmonization challenges for high-resolution metabolomics (HRM) data collected across different studies or analytical methods. Reference standardization relies on the concurrent analysis of calibrated pooled reference samples at p...

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Veröffentlicht in:	Analytical chemistry (Washington) 2020-07, Vol.92 (13), p.8836-8844
Hauptverfasser:	Liu, Ken H, Nellis, Mary, Uppal, Karan, Ma, Chunyu, Tran, ViLinh, Liang, Yongliang, Walker, Douglas I, Jones, Dean P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical methods Chemistry Chromatography, High Pressure Liquid High resolution Humans Hydrophobic and Hydrophilic Interactions Kynurenine - analysis Kynurenine - metabolism Kynurenine - standards Mass Spectrometry Mass spectroscopy Metabolites Metabolome Metabolomics Metabolomics - methods Metabolomics - standards Reference materials Reference Standards Reproducibility of Results Standardization Tryptophan - analysis Tryptophan - metabolism Tryptophan - standards
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