Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations
A subcommittee of the Hawaii Governor's Joint Task Force on Rat Lungworm Disease developed preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis (NAS) in 2018 (Guidelines, 2018). This paper reviews the main points of those guidelines and provides updates in areas whe...
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Veröffentlicht in: | Parasitology 2021-02, Vol.148 (2), p.227-233 |
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creator | Ansdell, Vernon Kramer, Kenton J. McMillan, Jourdan K. Gosnell, William L. Murphy, Gerald S. Meyer, B C Blalock, Elizabeth U. Yates, Johnnie Lteif, Louis Smith, Olivia A. Melish, Marian |
description | A subcommittee of the Hawaii Governor's Joint Task Force on Rat Lungworm Disease developed preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis (NAS) in 2018 (Guidelines, 2018). This paper reviews the main points of those guidelines and provides updates in areas where our understanding of the disease has increased. The diagnosis of NAS is described, including confirmation of infection by real-time polymerase chain reaction (RTi-PCR) to detect parasite DNA in the central nervous system (CNS). The treatment literature is reviewed with recommendations for the use of corticosteroids and the anthelminthic drug albendazole. Long-term sequelae of NAS are discussed and recommendations for future research are proposed. |
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This paper reviews the main points of those guidelines and provides updates in areas where our understanding of the disease has increased. The diagnosis of NAS is described, including confirmation of infection by real-time polymerase chain reaction (RTi-PCR) to detect parasite DNA in the central nervous system (CNS). The treatment literature is reviewed with recommendations for the use of corticosteroids and the anthelminthic drug albendazole. Long-term sequelae of NAS are discussed and recommendations for future research are proposed.</description><identifier>ISSN: 0031-1820</identifier><identifier>EISSN: 1469-8161</identifier><identifier>DOI: 10.1017/S0031182020001262</identifier><identifier>PMID: 32729438</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Albendazole ; Central nervous system ; Complications ; Corticoids ; Corticosteroids ; Diagnosis ; Diplopia ; Fever ; Guidelines ; Headaches ; Illnesses ; Infections ; Laboratories ; Medical diagnosis ; Meningitis ; Mollusks ; Pain ; Parasites ; Polymerase chain reaction ; Pruritus ; Pulmonary arteries ; Review ; Vomiting</subject><ispartof>Parasitology, 2021-02, Vol.148 (2), p.227-233</ispartof><rights>Copyright © The Author(s), 2020. Published by Cambridge University Press</rights><rights>Copyright © The Author(s), 2020. Published by Cambridge University Press. This work is licensed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (the “License”). 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This paper reviews the main points of those guidelines and provides updates in areas where our understanding of the disease has increased. The diagnosis of NAS is described, including confirmation of infection by real-time polymerase chain reaction (RTi-PCR) to detect parasite DNA in the central nervous system (CNS). The treatment literature is reviewed with recommendations for the use of corticosteroids and the anthelminthic drug albendazole. 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subjects | Albendazole Central nervous system Complications Corticoids Corticosteroids Diagnosis Diplopia Fever Guidelines Headaches Illnesses Infections Laboratories Medical diagnosis Meningitis Mollusks Pain Parasites Polymerase chain reaction Pruritus Pulmonary arteries Review Vomiting |
title | Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations |
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