Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations

A subcommittee of the Hawaii Governor's Joint Task Force on Rat Lungworm Disease developed preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis (NAS) in 2018 (Guidelines, 2018). This paper reviews the main points of those guidelines and provides updates in areas whe...

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Veröffentlicht in:Parasitology 2021-02, Vol.148 (2), p.227-233
Hauptverfasser: Ansdell, Vernon, Kramer, Kenton J., McMillan, Jourdan K., Gosnell, William L., Murphy, Gerald S., Meyer, B C, Blalock, Elizabeth U., Yates, Johnnie, Lteif, Louis, Smith, Olivia A., Melish, Marian
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container_end_page 233
container_issue 2
container_start_page 227
container_title Parasitology
container_volume 148
creator Ansdell, Vernon
Kramer, Kenton J.
McMillan, Jourdan K.
Gosnell, William L.
Murphy, Gerald S.
Meyer, B C
Blalock, Elizabeth U.
Yates, Johnnie
Lteif, Louis
Smith, Olivia A.
Melish, Marian
description A subcommittee of the Hawaii Governor's Joint Task Force on Rat Lungworm Disease developed preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis (NAS) in 2018 (Guidelines, 2018). This paper reviews the main points of those guidelines and provides updates in areas where our understanding of the disease has increased. The diagnosis of NAS is described, including confirmation of infection by real-time polymerase chain reaction (RTi-PCR) to detect parasite DNA in the central nervous system (CNS). The treatment literature is reviewed with recommendations for the use of corticosteroids and the anthelminthic drug albendazole. Long-term sequelae of NAS are discussed and recommendations for future research are proposed.
doi_str_mv 10.1017/S0031182020001262
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source Cambridge Journals; PubMed Central
subjects Albendazole
Central nervous system
Complications
Corticoids
Corticosteroids
Diagnosis
Diplopia
Fever
Guidelines
Headaches
Illnesses
Infections
Laboratories
Medical diagnosis
Meningitis
Mollusks
Pain
Parasites
Polymerase chain reaction
Pruritus
Pulmonary arteries
Review
Vomiting
title Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations
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