The role of carbon dioxide in acute brain injury

Carbon dioxide is a common gas in the air which has been widely used in medical treatment. A carbon dioxide molecule consists of two oxygen atoms and one carbon atom through a covalent bond. In the body, carbon dioxide reacts with water to produce carbonic acid. In healthy people, carbon dioxide is...

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Veröffentlicht in:Medical gas research 2020-04, Vol.10 (2), p.81-84
Hauptverfasser: Deng, Ru-Ming, Liu, Yong-Chun, Li, Jin-Quan, Xu, Jian-Guo, Chen, Gang
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Li, Jin-Quan
Xu, Jian-Guo
Chen, Gang
description Carbon dioxide is a common gas in the air which has been widely used in medical treatment. A carbon dioxide molecule consists of two oxygen atoms and one carbon atom through a covalent bond. In the body, carbon dioxide reacts with water to produce carbonic acid. In healthy people, carbon dioxide is maintained within a narrow range (35-45 mmHg) by physiological mechanisms. The role of hypocapnia (partial pressure of carbon dioxide < 35 mmHg) and hypercapnia (partial pressure of carbon dioxide > 45 mmHg) in the nervous system is intricate. Past researches mainly focus on the effect of hypocapnia to nerve protection. Nevertheless, Hypercapnia seems to play an important role in neuroprotection. The mechanisms of hypocapnia and hypercapnia in the nervous system deserve our attention. The purpose of this review is to summarize the effect of hypocapnia and hypercapnia in stroke and traumatic brain injury.
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subjects Apoptosis
Blood
Brain damage
Brain research
Carbon dioxide
Clinical outcomes
Edema
Health care
Hyperventilation
Hypoxia
Ischemia
Mortality
Physiology
Review
Stroke
Traumatic brain injury
Ventilators
title The role of carbon dioxide in acute brain injury
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