Neoantigen prediction and computational perspectives towards clinical benefit: recommendations from the ESMO Precision Medicine Working Group

The use of next-generation sequencing technologies has enabled the rapid identification of non-synonymous somatic mutations in cancer cells. Neoantigens are mutated peptides derived from somatic mutations not present in normal tissues that may result in the presentation of tumour-specific peptides c...

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Veröffentlicht in:	Annals of oncology 2020-08, Vol.31 (8), p.978-990
Hauptverfasser:	De Mattos-Arruda, L., Vazquez, M., Finotello, F., Lepore, R., Porta, E., Hundal, J., Amengual-Rigo, P., Ng, C.K.Y., Valencia, A., Carrillo, J., Chan, T.A., Guallar, V., McGranahan, N., Blanco, J., Griffith, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - genetics cancer Cancer Vaccines computational Humans Immunotherapy Medical Oncology mutation neoantigen Neoplasms - genetics Neoplasms - therapy personalised vaccine Practice Guidelines as Topic Precision Medicine
Online-Zugang:	Volltext
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