MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas

Objectives To assess the combined role of tumor vascularity, estimated from perfusion MRI, and MGMT methylation status on overall survival (OS) in patients with glioblastoma. Methods A multicentric international dataset including 96 patients from NCT03439332 clinical study were used to study the pro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European radiology 2021-03, Vol.31 (3), p.1738-1747
Hauptverfasser:	Fuster-Garcia, Elies, Lorente Estellés, David, Álvarez-Torres, María del Mar, Juan-Albarracín, Javier, Chelebian, Eduard, Rovira, Alex, Acosta, Cristina Auger, Pineda, Jose, Oleaga, Laura, Mollá-Olmos, Enrique, Filice, Silvano, Due-Tønnessen, Paulina, Meling, Torstein R., Emblem, Kyrre E., García-Gómez, Juan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Alkylating - therapeutic use Bias Blood volume Brain Neoplasms - diagnostic imaging Brain Neoplasms - drug therapy Brain Neoplasms - genetics Cerebral blood flow Diagnostic Radiology DNA Methylation DNA Modification Methylases - genetics DNA Repair Enzymes - genetics Glioblastoma Glioblastoma - diagnostic imaging Glioblastoma - genetics Humans Imaging Internal Medicine Interventional Radiology Magnetic resonance imaging Markers Medical prognosis Medicine Medicine & Public Health Methylation Neuroradiology Oncology Perfusion Prognosis Promoter Regions, Genetic Radiology Regression analysis Regression models Subpopulations Survival Temozolomide - therapeutic use Tumor Suppressor Proteins - genetics Tumors Ultrasound
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!