Energy Metabolism During Osteogenic Differentiation: The Role of Akt

Osteogenic differentiation, the process by which bone marrow mesenchymal stem/stromal (a.k.a. skeletal stem) cells and osteoprogenitors form osteoblasts, is a critical event for bone formation during development, fracture repair, and tissue maintenance. Extra cellular and intracellular signaling pat...

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Veröffentlicht in:	Stem cells and development 2021-02, Vol.30 (3), p.149-162
Hauptverfasser:	Smith, Charles Owen, Eliseev, Roman A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Bone Morphogenetic Protein 2 - metabolism Bone Morphogenetic Protein 2 - pharmacology Cell Differentiation - drug effects Cell Differentiation - physiology Cell Line Energy Metabolism - drug effects Energy Metabolism - physiology Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Mesenchymal Stem Cells - physiology Mice Mitochondria - metabolism Original Research Reports Osteoblasts - cytology Osteoblasts - metabolism Osteoblasts - physiology Osteogenesis - drug effects Osteogenesis - physiology Oxidative Phosphorylation Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-akt - physiology Signal Transduction - physiology Stem Cells - cytology Stem Cells - metabolism Stem Cells - physiology Wnt3A Protein - metabolism Wnt3A Protein - pharmacology
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