On the adhesion–velocity relation and length adaptation of motile cells on stepped fibronectin lanes

The biphasic adhesion–velocity relation is a universal observation in mesenchymal cell motility. It has been explained by adhesion-promoted forces pushing the front and resisting motion at the rear. Yet, there is little quantitative understanding of how these forces control cell velocity. We study m...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2021-01, Vol.118 (4), p.1-11
Hauptverfasser:	Schreiber, Christoph, Amiri, Behnam, Heyn, Johannes C. J., Rädler, Joachim O., Falcke, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Physical Sciences
Online-Zugang:	Volltext
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