High indoleamine-2,3-dioxygenase 1 (IDO) activity is linked to primary resistance to immunotherapy in non-small cell lung cancer (NSCLC)

Metabolic profiling in non-small cell lung cancer (NSCLC) may identify key metabolic vulnerabilities and shows enormous discovery potential. Preclinical studies showed that metabolic rewiring in cancer plays an essential role in modulation of immunotherapy response. However, this situation is unders...

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Veröffentlicht in:Translational lung cancer research 2021-01, Vol.10 (1), p.304-313
Hauptverfasser: Kocher, Florian, Amann, Arno, Zimmer, Kai, Geisler, Simon, Fuchs, Dietmar, Pichler, Renate, Wolf, Dominik, Kurz, Katharina, Seeber, Andreas, Pircher, Andreas
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Sprache:eng
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