Tumor Metabolic Reprogramming by Adipokines as a Critical Driver of Obesity-Associated Cancer Progression

Adiposity is associated with an increased risk of various types of carcinoma. One of the plausible mechanisms underlying the tumor-promoting role of obesity is an aberrant secretion of adipokines, a group of hormones secreted from adipose tissue, which have exhibited both oncogenic and tumor-suppres...

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Veröffentlicht in:	International journal of molecular sciences 2021-02, Vol.22 (3), p.1444
Hauptverfasser:	Pham, Duc-Vinh, Park, Pil-Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidification Adipocytes Adiponectin Adipose tissue Angiogenesis Autophagy Biosynthesis Breast cancer Cell adhesion & migration Cell cycle Crosstalk Cytokines Glucose metabolism Hypoxia Kinases Leptin Lipid metabolism Lipids Liver cancer Medical prognosis Metabolism Metabolites Metastasis Obesity Phenotypes Phosphorylation Proteins Review Rewiring Roles Tumor cells Tumor microenvironment Tumorigenesis Tumors
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