High-Fat Diet and Age-Dependent Effects of IgA-Bearing Cell Populations in the Small Intestinal Lamina Propria in Mice

Several studies highlighted that obesity and diabetes reduce immune function. However, changes in the distribution of immunoglobins (Igs), including immunoglobulin-A (IgA), that have an important function in mucosal immunity in the intestinal tract, are unclear. This study aimed to investigate the i...

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Veröffentlicht in:	International journal of molecular sciences 2021-01, Vol.22 (3), p.1165
Hauptverfasser:	Sakamoto, Yuta, Niwa, Masatoshi, Muramatsu, Ken, Shimo, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Animal models Animals Blood Glucose Body Weight Communication Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - etiology Diabetes Mellitus, Type 2 - metabolism Diet Diet, High-Fat Disease Models, Animal Glucose High fat diet Hypotheses Immune response Immunity, Mucosal Immunoglobulin A Immunoglobulin A - immunology Immunoglobulin G Immunoglobulin M Immunohistochemistry Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Intestine Lamina propria Mice Microbiota Microscopy Mucosal immunity Obesity Obesity - etiology Obesity - metabolism Overweight Proteins
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