Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies

The advent of immunotherapy has transformed the treatment landscape for several human malignancies. Antibodies against immune checkpoints, such as anti-PD-1/PD-L1 and anti-CTLA-4, demonstrate durable clinical benefits in several cancer types. However, checkpoint blockade has failed to elicit effecti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancers 2021-01, Vol.13 (3), p.440
Hauptverfasser:	Pham, Thao N D, Shields, Mario A, Spaulding, Christina, Principe, Daniel R, Li, Bo, Underwood, Patrick W, Trevino, Jose G, Bentrem, David J, Munshi, Hidayatullah G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Animal models Antibodies Antigens Cancer therapies Chemotherapy CTLA-4 protein FDA approval Immune checkpoint Immunotherapy Ligands Lymphocytes Melanoma Metastasis Mutation Organoids Pancreas PD-1 protein PD-L1 protein Review T cell receptors Tumors Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!