Efficient detection and post-surgical monitoring of colon cancer with a multi-marker DNA methylation liquid biopsy

Multiplex assays, involving the simultaneous use of multiple circulating tumor DNA (ctDNA) markers, can improve the performance of liquid biopsies so that they are highly predictive of cancer recurrence. We have developed a single-tube methylation-specific quantitative PCR assay (mqMSP) that uses 10...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2021-02, Vol.118 (5), p.1-8
Hauptverfasser:	Jin, Shengnan, Zhu, Dewen, Shao, Fanggui, Chen, Shiliang, Guo, Ying, Li, Kuan, Wang, Yourong, Ding, Rongxiu, Gao, Lingjia, Ma, Wen, Lu, Tong, Li, Dandan, Zhang, Zhengzheng, Cai, Suili, Liang, Xue, Song, Huayu, Ji, Ling, Li, Jinlei, Zheng, Zhihai, Jiang, Feizhao, Wu, Xiaoli, Luan, Ju, Zhang, Huxiang, Yang, Zhengquan, Cantor, Charles R., Xu, Chang, Ding, Chunming
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences
Online-Zugang:	Volltext
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