JMJD2C triggers the growth of multiple myeloma cells via activation of β‑catenin

Emerging evidence has indicated that histone modification and its related regulators are involved in the progression of multiple myeloma (MM) cells. In the present study, the expression of Jumonji C domain‑containing 2 (JMJD2) was examined in both MM tissues and healthy controls. The roles of JMJD2C...

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Veröffentlicht in:	Oncology reports 2021-03, Vol.45 (3), p.1162-1170
Hauptverfasser:	Lv, Ming, Liu, Qicai
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens beta Catenin - antagonists & inhibitors beta Catenin - genetics beta Catenin - metabolism Biomarkers, Tumor - metabolism Biotechnology Bone marrow Cancer therapies Case-Control Studies Cell adhesion & migration Cell Line, Tumor Cell Proliferation - drug effects Cell Proliferation - genetics DNA Demethylation Epigenesis, Genetic Epigenetics Female Gene expression Gene Expression Regulation, Neoplastic Glycogen Synthase Kinase 3 beta - antagonists & inhibitors Glycogen Synthase Kinase 3 beta - metabolism Healthy Volunteers Histone Code Humans Jumonji Domain-Containing Histone Demethylases - metabolism Kaplan-Meier Estimate Kinases Laboratories Male Medical prognosis Middle Aged Multiple myeloma Multiple Myeloma - mortality Multiple Myeloma - pathology Multiple Myeloma - surgery Patients Phosphorylation Plasma Promoter Regions, Genetic Proteins Wnt Signaling Pathway - drug effects Wnt Signaling Pathway - genetics
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