DDX41 regulates the expression and alternative splicing of genes involved in tumorigenesis and immune response

DEAD‑box helicase 41 (DDX41) is an RNA helicase and accumulating evidence has suggested that DDX41 is involved in pre‑mRNA splicing during tumor development. However, the role of DDX41 in tumorigenesis remains unclear. In order to determine the function of DDX41, the human DDX41 gene was cloned and...

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Veröffentlicht in:	Oncology reports 2021-03, Vol.45 (3), p.1213-1225
Hauptverfasser:	Qin, Kai, Jian, Danni, Xue, Yaqiang, Cheng, Yi, Zhang, Peng, Wei, Yaxun, Zhang, Jing, Xiong, Huihua, Zhang, Yi, Yuan, Xianglin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biotechnology Cancer Cell growth Cloning Comparative analysis Deoxyribonucleic acid DNA Enzymes Ethylenediaminetetraacetic acid Gene expression Genes Genetic engineering Histocompatibility antigens HLA histocompatibility antigens Immune response International economic relations Kinases Leukemia Messenger RNA Mutation Plasmids Proteins Scientific equipment and supplies industry Tumorigenesis Tumors
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