Reorganization of functional brain network architecture in chronic osteoarthritis pain

Osteoarthritis (OA) manifests with chronic pain, motor impairment, and proprioceptive changes. However, the role of the brain in the disease is largely unknown. Here, we studied brain networks using the mathematical properties of graphs in a large sample of knee and hip OA (KOA, n = 91; HOA, n = 23)...

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Veröffentlicht in:	Human brain mapping 2021-03, Vol.42 (4), p.1206-1222
Hauptverfasser:	Barroso, Joana, Wakaizumi, Kenta, Reis, Ana Mafalda, Baliki, Marwan, Schnitzer, Thomas J., Galhardo, Vasco, Apkarian, Apkar Vania
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arthralgia - diagnostic imaging Arthralgia - etiology Arthralgia - physiopathology Arthritis Biomedical materials Brain Brain architecture brain networks brain topology Cerebral Cortex - diagnostic imaging Cerebral Cortex - physiopathology Chronic pain Chronic Pain - diagnostic imaging Chronic Pain - etiology Chronic Pain - physiopathology Computer architecture Connectome Cortex (insular) Cortex (somatosensory) Disruption Female graph properties Hip Hubs Humans Magnetic Resonance Imaging Male Middle Aged Nerve Net - diagnostic imaging Nerve Net - physiopathology Network hubs Neural networks Osteoarthritis Osteoarthritis, Hip - complications Osteoarthritis, Hip - physiopathology Osteoarthritis, Knee - complications Osteoarthritis, Knee - physiopathology Pain Pain perception Parahippocampal gyrus Parameter identification Properties (attributes) Proprioception Robustness (mathematics) Topology
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