Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation

The translation machinery is composed of a myriad of proteins and RNAs whose levels must be coordinated to efficiently produce proteins without wasting energy or substrate. However, protein synthesis is clearly not always perfectly tuned to its environment, as disruption of translation machinery com...

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Veröffentlicht in:Current biology 2021-01, Vol.31 (1), p.128-137.e5
Hauptverfasser: Itani, Omar A., Zhong, Xuefei, Tang, Xiaoting, Scott, Barbara A., Yan, Jun Yi, Flibotte, Stephane, Lim, Yiting, Hsieh, Andrew C., Bruce, James E., Van Gilst, Marc, Crowder, C. Michael
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