PICH regulates the abundance and localization of SUMOylated proteins on mitotic chromosomes

Proper chromosome segregation is essential for faithful cell division and if not maintained results in defective cell function caused by the abnormal distribution of genetic information. Polo-like kinase 1-interacting checkpoint helicase (PICH) is a DNA translocase essential for chromosome bridge re...

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Veröffentlicht in:	Molecular biology of the cell 2020-11, Vol.31 (23), p.2537-2556
Hauptverfasser:	Hassebroek, Victoria A, Park, Hyewon, Pandey, Nootan, Lerbakken, Brooklyn T, Aksenova, Vasilisa, Arnaoutov, Alexei, Dasso, Mary, Azuma, Yoshiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Centromere - metabolism Chromosome Segregation - genetics Chromosome Segregation - physiology Chromosomes - metabolism DNA Helicases - metabolism DNA Helicases - physiology DNA Topoisomerases, Type II - metabolism DNA-Binding Proteins - metabolism Humans Mitosis - genetics Mitosis - physiology Sumoylation
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