Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas

While the anti-PDGFRA antibody olaratumab failed to confirm an impact on survival in unselected advanced soft tissue sarcoma (STS) patients, the level of expression and the prognosis of platelet-derived growth factor (PDGF) receptors and ligands in STS remain unclear. We analyzed PDGF ligands and re...

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Veröffentlicht in:	ESMO open 2021-02, Vol.6 (1), p.100037-100037, Article 100037
Hauptverfasser:	Brahmi, M., Lesluyes, T., Dufresne, A., Toulmonde, M., Italiano, A., Mir, O., Le Cesne, A., Valentin, T., Chevreau, C., Bonvalot, S., Penel, N., Coindre, J.-M., Le Guellec, S., Le Loarer, F., Karanian, M., Blay, J.-Y., Chibon, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	expression level Humans Life Sciences Ligands Liposarcoma, Myxoid Lymphokines Neoplasm Recurrence, Local Original Research PDGF PDGFR Platelet-Derived Growth Factor Prognosis prognostic factor Proto-Oncogene Proteins c-sis Receptor, Platelet-Derived Growth Factor beta - genetics sarcoma Sarcoma - genetics
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