Distribution of β-Lactamase Genes and Genetic Context of blaKPC-2 in Clinical Carbapenemase-Producing Klebsiella pneumoniae Isolates

Background: This study was designed to characterize the dissemination mechanism and genetic context of Klebsiella pneumoniae carbapenemase (KPC) genes in carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates. Methods: A retrospective analysis was performed on CRKP strains isolated from a teachi...

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Veröffentlicht in:	Infection and drug resistance 2021-01, Vol.14, p.237-247
Hauptverfasser:	Liu, Hongmao, Lin, Hailong, Sun, Zhewei, Zhu, Xinyi, Zhang, Xueya, Li, Qiaoling, Lu, Junwan, Lin, Xi, Lin, Li, Li, Kewei, Zhu, Mei, Bao, Qiyu, Xu, Teng, Hu, Yunliang, Zhang, Hailin
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic resistance Antibiotics Antimicrobial agents Antimicrobial resistance Bacterial infections blakpc-2 Carbapenemase Chromosomes Cloning Conjugation crkp Deoxyribonucleic acid DNA Drug resistance Gel electrophoresis Gene mapping Genes Genomes Genomics Infectious Diseases Klebsiella pneumoniae kpc-kp Life Sciences & Biomedicine Multidrug resistance Multilocus sequence typing Original Research Pharmacology & Pharmacy Plasmids Polymerase chain reaction Proteins Pulsed-field gel electrophoresis Science & Technology st11 Strains (organisms) tn1721 Transposons Whole genome sequencing β Lactamase
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