Hepatic thermal injury promotes colorectal cancer engraftment in C57/black 6 mice

Treatment options for liver metastases (primarily colorectal cancer) are limited by high recurrence rates and persistent tumor progression. Surgical approaches to management of these metastases typically use heat energy including electrocautery, argon beam coagulation, thermal ablation of surgical m...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2021-01, Vol.320 (1), p.C142-C151, Article ajpcell.00071.2020
Hauptverfasser:	Halpern, Alison L, Fitz, J Gregory, Fujiwara, Yuki, Yi, Jeniann, Anderson, Aimee L, Zhu, Yuwen, Schulick, Richard D, El Kasmi, Karim C, Barnett, Jr, Carlton C
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Adenocarcinoma - metabolism Adenocarcinoma - secondary Animals Arginase Arginase - genetics Arginase - metabolism Burns, Electric - genetics Burns, Electric - metabolism Burns, Electric - pathology Cell activation Cell Line, Tumor Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Colorectal cancer Colorectal carcinoma Cytokines Disease Models, Animal Disease Progression Hemostasis Hypoxia-Inducible Factor 1, alpha Subunit - genetics Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Hypoxia-inducible factors Liver - metabolism Liver - pathology Liver cancer Liver Neoplasms - metabolism Liver Neoplasms - secondary Macrophage Activation Macrophages Metastases Metastasis Mice Mice, Inbred C57BL Microenvironments mRNA Neoplasm Transplantation Signal Transduction Thermal injury Tumor Microenvironment Tumors Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism
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