Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer

Comprehensive genomic analyses of small cell lung cancer (SCLC) have revealed frequent mutually exclusive genomic amplification of MYC family members. Hence, it has been long suggested that they are functionally equivalent; however, more recently, their expression has been associated with specific n...

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Veröffentlicht in:Science advances 2021-01, Vol.7 (5)
Hauptverfasser: Patel, Ayushi S, Yoo, Seungyeul, Kong, Ranran, Sato, Takashi, Sinha, Abhilasha, Karam, Sarah, Bao, Li, Fridrikh, Maya, Emoto, Katsura, Nudelman, German, Powell, Charles A, Beasley, Mary Beth, Zhu, Jun, Watanabe, Hideo
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Sprache:eng
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