Application of a Framework for Grouping and Mixtures Toxicity Assessment of PFAS: A Closer Examination of Dose-Additivity Approaches

Abstract Environmental occurrence and biomonitoring data for per- and polyfluoroalkyl substances (PFAS) demonstrate that humans are exposed to mixtures of PFAS. This article presents a new and systematic analysis of available PFAS toxicity study data using a tiered mixtures risk assessment framework...

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Veröffentlicht in:	Toxicological sciences 2021-01, Vol.179 (2), p.262-278
Hauptverfasser:	Goodrum, Philip E, Anderson, Janet K, Luz, Anthony L, Ansell, Graham K
Format:	Artikel
Sprache:	eng
Schlagworte:	Regulatory Science, Risk Assessment, and Decision Making
Online-Zugang:	Volltext
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