Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa

Antibiotic-resistant bacteria rapidly spread in clinical and natural environments and challenge our modern lifestyle. A major component of defense against antibiotics in Gram-negative bacteria is a drug permeation barrier created by active efflux across the outer membrane. We identified molecular de...

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Veröffentlicht in:	mBio 2021-01, Vol.12 (1), Article 02785
Hauptverfasser:	Mehla, Jitender, Malloci, Giuliano, Mansbach, Rachael, Lopez, Cesar A., Tsivkovski, Ruslan, Haynes, Keith, Leus, Inga, Grindstaff, Sally B., Cascella, Robert H., D'Cunha, Napoleon, Herndon, Liam, Hengartner, Nicolas W., Margiotta, Enrico, Atzori, Alessio, Vargiu, Attilio V., Manrique, Pedro D., Walker, John K., Lomovskaya, Olga, Ruggerone, Paolo, Gnanakaran, S., Rybenkov, Valentin V., Zgurskaya, Helen
Format:	Artikel
Sprache:	eng
Schlagworte:	antibiotic resistance BASIC BIOLOGICAL SCIENCES Life Sciences & Biomedicine machine learning models Microbiology multidrug efflux outer membrane Pseudomonas aeruginosa Research Article Science & Technology Therapeutics and Prevention
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